Remember to keep your Cancer Details Checklist handy to help you answer some of the questions that may be asked. It is used to learn whether … This is a randomized, 2-arm, Phase 3, open-label, multicenter study to compare the safety and efficacy of trastuzumab deruxtecan versus the physician's choice (2:1) in HER2-low, unresectable and/or metastatic breast cancer participants. Find a clinical trial. Wearing masks helps us keep each other safe. Look carefully at how often you will need to receive treatment during the course of the trial. CenterWatch. What is the main purpose of the trial? It contains trials that are in NCI's list of cancer trials as well as trials sponsored by pharmaceutical or biotech companies that may not be on NCI's list. Watch this quick overview of how to search for an NCI-supported clinical trial. The purpose of this study is to assess the efficacy and safety of pembrolizumab vsersus placebo in combination with neoadjuvant (pre-surgery) chemotherapy and adjuvant (post-surgery) endocrine therapy in the treatment of adults who have high-risk early-stage estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+/HER2-) breast cancer. Doctors use clinical trials to develop new treatments for serious diseases such as cancer. You can also get help from a clinical trial navigator through their website. ymgerman/iStock. Not all protocol summaries provide this information. If you’ve been diagnosed with cancer, a clinical trial may offer access to the latest and most promising science, while helping to light the path for future survivors. It is not yet known whether doxorubicin hydrochloride and cyclophosphamide are more effective when followed by paclitaxel alone or paclitaxel and carboplatin in treating triple-negative breast cancer. These organizations generally do not sponsor or take part in clinical trials. Stephenson Cancer Center currently has approximately 300 active clinical trials for all types and stages of cancer – more than any other center in … Use the tool below to find a CTCA ® clinical trial for your cancer type. Clinical trials provide important alternative … In this section you can learn about clinical trials in general, find tools to help you decide if a clinical … This is a free service. You may decide that joining a trial is your best option, or you may decide not to join a trial. The GENERATE Study is also open across the United States for people who have a close relative with pancreatic cancer… A phase 3 multi-center, randomized, open-label trial to evaluate the efficacy and safety of ribociclib with endocrine therapy as adjuvant treatment in patients with HR-positive, HER2-negative early breast cancer. Learn more about specific Lustgarten Foundation and Stand Up To Cancer-supported clinical trials by utilizing our clinical trial finder below. If so, you may want to get a second opinion about your treatment options, including taking part in a clinical trial. There are a few ways to reach the clinical trial team. Many companies provide lists of the clinical trials that they sponsor on their websites. Some will have information about clinical trials that are enrolling patients. World … This guide takes you through the following steps: If you decide to look for a clinical trial, you will need to know certain details about your cancer diagnosis and compare these details with the eligibility criteria of any trial that interests you. You may want to talk with your doctor or another health care team member during this process, especially if you find the protocol summaries hard to understand. You can also always call 1-800-4-CANCER (1-800-422-6237) to speak with an NCI cancer information specialist in English or Spanish. Some doctors may not be aware of or recommend clinical trials that could be appropriate for you. ClinicalTrials.gov is a resource provided by the U.S. National Library of Medicine. To reach them call 1-800-4-CANCER (1-800-422-6237) and select option 2. Some of them may receive fees from drug or biotechnology companies for listing their trials or helping find patients for their trials. Keep the following points in mind about clinical trial listing services: Cancer advocacy groups provide education, support, financial assistance, and advocacy to help patients and families who are dealing with cancer, its treatment, and survivorship. After thinking about these questions, if you are still interested in a clinical trial, then you are ready to contact the team running the trial. Keep in mind that the search … Take a closer look at the protocol summary for each trial, Use the questions below to narrow your list to include only those trials for which you would like to get more information. To make a final decision, you will want to know the potential risks and benefits of all treatment options available to you. Search by cancer type, drug name, trial name, or choose from a list of cancer types. Or, you can contact an advocacy group directly for help finding clinical trials. If you decide to join a clinical trial for which you are eligible, schedule a visit with the team running the trial. CRI Clinical Trial Finder Cancer immunotherapy clinical trials are critical to bringing new and potentially lifesaving treatments to more patients with more types of cancer, and may … Drugs used in chemotherapy, such as doxorubicin hydrochloride, cyclophosphamide, paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Other treatment trials are looking for people who have already been treated for their cancer. This randomized phase III trial studies how well doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carboplatin work in treating patients with triple-negative breast cancer. Answering a simple series of questions allows us to find relevant trials that fit your needs. Find a Clinical Trial. Home About Cancer Find a clinical trial. Others are funded by for-profit groups, such as drug companies. Sometimes, a company's website may refer you to the website of another organization that helps the company find patients for its trials. Keep in mind that the amount of information about clinical trials on these websites can vary. They will need to know details about your cancer, so have your Cancer Details Checklist ready. Decide how far and how often you are willing to travel. December 04, 2020. Once you have completed the Cancer Details Checklist and found some trials that interest you, you should now: Helpful Tip: Don't worry if you can't answer all of the questions below just yet. NIH conducts clinical research trials for many diseases and conditions, including cancer, … For help understanding the protocol summary, call, email, or chat with one of our cancer information specialists. Then, you and your doctor can compare the risks and benefits of standard treatment with those of treatment in a clinical trial. IMPORTANT: Listing a study does not mean it has been evaluated by the U.S. Federal Government.Read our … This includes enrolling qualified patients in carefully selected clinical trials … He or she may also be able to search for a trial for you, provide information, and answer questions to help you decide about joining a clinical trial. To determine whether a new treatment is safe and well-tolerated? Cancer Clinical Trials Research is changing the way cancer is being treated. The best way to find a clinical trial for you is to talk to your doctor. Talk with your doctor about how quickly you need to make a treatment decision. The other organization may be paid fees for this service. Cancer trials may offer patients access to treatment options that would otherwise be unavailable to them. There are two … Our doctors may recommend that cancer patients enroll in cancer … The National Cancer Institute explains in depth below: Patient Care Costs: These are general costs related to treating your cancer. Our doctors may recommend that cancer patients enroll in cancer clinical trials if they meet specific criteria. Learn how to find the right clinical trial for you with the National Cancer Institute's six-step guide. Some treatment trials will not accept people who have already been treated for their cancer. Cancer Treatment Centers of America® (CTCA) is committed to providing new and innovative treatments for our cancer patients whenever possible. This includes enrolling qualified patients in carefully selected clinical trials for cancer. A protocol summary should explain the goal of the trial and describe which treatments will be tested. Tax-ID: 73-1386920, A randomized, phase II study of nivolumab after combined modality therapy (CMT) in high-risk anal cancer (EA2165), S1815: A phase III randomized trial of gemcitabine, cisplatin and nab-paclitaxel versus gemcitabine and cisplatin in newly diagnosed, advanced biliary tract cancers, An open-label, randomized, phase 2 trial of SAR439859, versus endocrine monotherapy as per physician's choice in premenopausal and postmenopausal patients with estrogen receptor-positive, HER2-negative locally advanced or metastatic breast cancer with prior exposure to hormonal therapies (ACT16105), Merck KEYNOTE-756: A randomized, double-blind, phase 3 study of pembrolizumab versus placebo in combination with neoadjuvant chemotherapy and adjuvant endocrine therapy for the treatment of high-risk, early-stage estrogen receptor-positive, human epidermal growth factor receptor 2-negative breast cancer, NRG-BR002: A phase IIR/III trial of standard-of-care therapy with or without stereotactic body radiotherapy (SBRT) and/or surgical ablation for newly oligometastatic breast cancer, DS8201-A-U303 (DESTINY-Breast04): A Phase 3, multicenter, randomized, open-label, active-controlled trial of DS-8201a, an anti-HER2-antibody drug conjugate (ADC), versus treatment of physician’s choice for HER2-low, unresectable and/or metastatic breast cancer subjects, NRG-BR003: A randomized phase III trial of adjuvant therapy comparing doxorubicin plus cyclophosphamide followed by weekly paclitaxel with or without carboplatin for node-positive or high-risk node-negative triple-negative invasive breast cancer, Testing MK-3475 (pembrolizumab) as adjuvant therapy for triple receptor-negative breast cancer (S1418), Novartis CLEE011012301C: A phase 3, multi-center, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive, HER2-negative early breast cancer (new adjuvant trial with ribociclib [LEE011]: NATALEE), NRG-BR004: A randomized, double-blind, phase III trial of paclitaxel/trastuzumab/pertuzumab with atezolizumab or placebo in first-line HER2-positive metastatic breast cancer. The purpose of this study is to evaluate the activity of SAR439859, a potent, orally bioavailable, and selective estrogen receptor (ER) inhibitor that belongs to the selective estrogen receptor degrader (SERD) class of compounds in comparison with other endocrine treatments approved for the treatment of breast cancer, including fulvestrant, selective ER modulators (tamoxifen), and AIs (anastrozole, exemestane, and letrozole). To reach them call 1-800-4-CANCER (1-800-422-6237) and select option 2. Many cancer advocacy groups offer help in finding clinical trials that might be a good fit for you. This randomized phase III trial studies how well paclitaxel, trastuzumab, and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body. Is it to cure your cancer? You may have to contact a cancer center clinical trials office to get more information about the trials that interest you. Around 32% of 80,000 brain tumors diagnosed per year in the U.S. turn out to be cancerous. Sort by: Breast Cancer . What are Clinical Trials? Find a clinical trial at The University of Kansas Cancer Center in Kansas City. Trials aim to find … The Cancer Clinical Trial Finder app is now available for the iPhone on the IOS App Store and Android on Google Play. Helpful Hint: If you have just found out that you have cancer, the time to think about joining a trial is before you have any treatment. If you are in a community cancer center or private practice setting, you may need to ask your doctor whether there are any clinical trials … Clinical trials are a key testing ground for determining the effectiveness and safety of new treatments and drugs for cancer and other diseases. If you have any remaining questions or concerns, you should discuss them with your doctor. It's your choice. This organizationprovides infor… How do I find a pancreatic cancer clinical trial? You will receive potential research study matches. PhRMA is a trade organization that represents drug and biotechnology companies in the United States. Questions to Ask Your Doctor about Treatment Clinical Trials can help you think about questions you want to ask. Some of the trials included in these lists may not be on NCI's list. Find Cancer Clinical Trials Cancer immunotherapy clinical trials are critical to bringing new and potentially lifesaving treatments to more patients with more types of cancer, and may … What clinical trials are. How to Find a Cancer Clinical Trial. You will need to refer to the Cancer Details Checklist during this conversation, so keep it handy. Cancer Center Launches Clinical Trial Finder App. The list includes: If you need help with your search, you can call, email, or chat with one of our trained information specialists. This randomized phase II clinical trial studies how well nivolumab after combined modality therapy works in treating patients with high risk stage II-IIIB anal cancer. Because many of these groups focus on a specific type of cancer, they can help you find trials for your type of cancer. If you are being treated in an academic medical center or large cancer center, the discussion about participating in clinical trials usually takes place early in the process. Voiceover: A clinical trial is a medical research study that involves volunteers and helps doctors find better treatments for cancer. Cancer.Net: Doctor-Approved Patient Information from ASCO® How to Find a Clinical Trial for Cancer Treatment. Make a difference in the fight against cancer by donating to cancer research, Gateway for Cancer Research is a 501(c)(3) non-profit organization. NCI's website helps you find NCI-supported clinical trials that are taking place across the United States, Canada, and internationally. However, don't give up on trials you're not sure about. To request their help, complete the online form. There are many lists of cancer clinical trials taking place in the United States. Because of the many types of sponsors, no single list contains every clinical trial. Ask your doctor some of the same questions that you asked the trial coordinator. If they do, consider the time involved and whether it will work for you and your family. The staff at CISCRPwill conduct free clinical trial searches. … Keep in mind that the search results do not replace advice from your doctor. Many of these websites have lists of clinical trials or refer you to the websites of organizations that match patients to trials. The websites of these centers usually have a list of the clinical trials taking place at their institutions. Around the Nation and Worldwide. Other places to look for lists of cancer clinical trials include: ClinicalTrials.gov, which is part of the National Library of Medicine, lists clinical trials for cancer and many other diseases and conditions. To lessen the severity of cancer symptoms or the side effects of treatment? The following organizations listed in alphabetical order offer free, searchable listings of cancer clinical trials. Clinical trials connect patients with cutting-edge treatment options while also participating in the process to look for better ways to prevent, diagnose, or treat cancer… Finding a Clinical Trial. Cancer Centers and Clinics that Conduct Cancer Clinical Trials. Find Brain Cancer Clinical Trials With DoNotPay—The Fast and Easy Way. Complementary & Alternative Medicine (CAM), Coping with Your Feelings During Advanced Cancer, Emotional Support for Young People with Cancer, Young People Facing End-of-Life Care Decisions, Late Effects of Childhood Cancer Treatment, Tech Transfer & Small Business Partnerships, Frederick National Laboratory for Cancer Research, Milestones in Cancer Research and Discovery, Step 1: Application Development & Submission, How to Work With Your Health Insurance Plan, Questions to Ask about Treatment Clinical Trials, Drugs Approved for Different Types of Cancer, Drugs Approved for Conditions Related to Cancer, call, email, or chat with one of our cancer information specialists, NCI Community Oncology Research Program (NCORP), Experimental Therapeutics Clinical Trials Network (ETCTN), NIH Clinical Center in Bethesda, Maryland, Questions to Ask Your Doctor about Treatment Clinical Trials, U.S. Department of Health and Human Services, Having received (or not having received) a certain type of treatment in the past. Clinical trials can offer people with cancer … Find an NCI-supported clinical trial—and learn how to locate other research studies—that may be right for you or a loved one. It should also list the locations where the trial is taking place. Some trials are funded by nonprofit organizations, including the U.S. government. These organizations recognize that clinical trials are important to improving cancer care. You should also ask your doctor about the risks and benefits of standard treatment for your cancer. Eligibility criteria are the requirements that must be met for you to join a clinical trial. Advocacy groups work hard to know about the latest advances in cancer research. The NCI 's Cancer Information Service can also provide a tailored clinical trials search that you can discuss with your doctor. Some organizations provide lists of clinical trials as a part of their business. This randomized phase III trial studies how well pembrolizumab works in treating patients with triple-negative breast cancer. Learn more and talk to your doctor to see if a clinical trial … Skip to main content 1-800-4-CANCER Live Chat Publications … … CTCA Atlanta CTCA Chicago CTCA Philadelphia CTCA Phoenix . Helpful Tip: Whichever website you use to search for clinical trials, be sure to bookmark or print a copy of the protocol summary for every trial that interests you. If you are thinking about joining a clinical trial as a treatment option, the best place to start is to talk with your doctor or another member of your health care team. Is the location of the trial manageable for you? How long will the trial run? Find a trial. ... Central Vermont Medical Center participates in clinical trials as an affiliate of the University of Vermont Cancer Center. In addition to NCI's list of cancer clinical trials, you may want to check a few other trial lists. Some trials take place at more than one location. Keep in mind that protocol summaries are written for health care providers and use medical language to describe the trial that may be difficult to understand. Hospitals and academic medical centers also sponsor trials conducted by their own researchers. This includes enrolling qualified patients in carefully selected clinical trials for cancer. Talk to your doctor about whether a cancer trial is a good option for you and ask about the risks and various requirements involved. Masks are Required. All NCI network trials, including trials supported through the: Trials that are funded in full or in part by NCI, including trials taking place at. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Usually have a list of cancer clinical trials that are taking place in United... 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