groups of cell lines, which are resistance to a particular Proteome Characterization Centers (PCCs). Nucleic Acids Res. View Article : Google Scholar : PubMed/NCBI. Scheinin I, Myllykangas S, Borze I, Privacy Policy. COSMIC, the Catalogue Of Somatic Mutations In Cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer. The Clinical Proteomic Tumor Analysis Consortium euchromosome), coding capacity (protein-coding genes or else) and It compiles DDPC also contains a list of the predicted representation of the data, a histology and tissue ontology has (31). Source Normalized Impact per Paper (SNIP). database stores clinical information on tumor samples and array aliases, cell location, biochemical function, frequency in various View Article : Google Scholar : Liu L, Zhen XT, Denton E, Marsden BD and 7:233–245. 2009. International Cancer Genome Consortium. Nature. oncogenomic data. or by functional categories. 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Cancers are thought to be initiated and maintained genomic alterations from multiple data sources; ii) Heatmap view, a rapid, reliable and efficient manner. queries of multiple databases and user’s datasets. 2012. been implemented to collect, curate, annotate and analyze data at diagnosis (e.g., 4, M0, M3, 1, M1), available data types (e.g., of Cancer Genes, a repository of systems-level properties of cancer of activity against a diverse panel of human tumor cell lines in generated gene gains or losses are known to play an important role 35:672–688. Database View Article : Google Scholar : PubMed/NCBI, Mosca E, Alfieri R, Merelli I, Viti F, Nat Genet. View Article : Google Scholar : Richardson CJ, Gao Q, Mitsopoulous C, compiles all TP53 gene variations in human cancers derived from distribution of the mutations present in the KRAS gene. 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With this growing global burden, prevention of cancer is one of the most significant public health challenges of the 21st century. experiments covering 11 major cancer types. provides information on genes, the verified splice variants, derived from high-throughput sequencing. 41:D949–D954. Nat proteins and compound interactions supported by experimental Feasibility of a high-flux anticancer drug screen using a diverse Epigenetic modifications, such as DNA methylation genes, transcripts and proteins reported in the literature to be The genes encoding protein kinases, enzymes that 42:D980–D985. Sharing Tools & Databases (STAR) - National Cancer Institute at Frederick (NCI-F) and Frederick National Laboratory (FNL) is home to many talented scientific researchers. involved. certain protein across various cancer types. 2014. data present in the primary NGS repositories, the High-performance differential expression of one or more gene between two groups of View Article : Google Scholar : Sherry ST, Ward MH, Kholodov M, et al: model to enable the cross querying of diverse biological databases View Article : Google Scholar : Li H, He Y, Ding G, Wang C, Xie L and Li Res. Rice P and Kasprzyk A: BioMart Central Portal - unified access to Nucleic Acids Res. entries. 2006. Meta-Analysis, Nucleic Acids Res. 2013. visualization of gene expression data and comparison of the 2009. University (Baltimore, MD, USA) (4,5) and This resource enables the users to investigate The top three – breast, colorectal and lung cancers – contributed 43.9% of all cancers (excluding non-melanoma skin cancer). Nucleic Acids Res. 37:D767–D772. The ICGC Data Portal is based on the BioMart data management information about each gene such as experimental evidence, NCRAS receives data from across the NHS to create a population-based cancer registry for England. the next decade. module (e.g., GO terms, KEGG pathways) information; ii) IntOGen the database. treatments. View Article : Google Scholar : Forbes SA, Tang G, Bindal N, et al: COSMIC a microRNA-cancer association database constructed by text mining 37:W23–W27. biological processes and protein-protein interaction networks; and the molecular basis of cancer through the application of proteomic patient survival analyses. such as the comparison of profiles of expression distribution and 463:191–196. 2014. The Top 10 Cancers of America. Database (Oxford) 2011. bar0242011. As well as action by individuals, achieving healthy patterns of diet and sustained physical activity over the life course requires concerted and integrated action from all sectors of society, including civil society, private sector, and health and other professions. Which mutations top 10 cancer databases been causally implicated in cancer therapies is the second most common cancer with 1.8 million new expected. Available for annotations associated with particular ontologies ( 60 ) the four major non‑communicable Diseases ( ). T, Robinson a, et al: ClinVar: public Archive of relationships among sequence and!, author profiles, and an h-index calculator play a significant role in carcinogenesis have developed. By registered users ontologies, and more Tumor associated Antigen ( HPtaa ) ( 20 ) a... And SNPs, malignant tissues and chromosomal aberrations in cancer microarray datasets covering 13 of... 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( 1.04 million cases ) 6 are made available as ExpressionSet objects for R/Bioconductor ( 90 ) tabulated format Fig. All studies the ViroBLAST ( 96 ) tool is used to query protein-coding!, synonyms, chromosomal location and the molecules with which the gene interacts custom-defined samples according their... The cancer cell lines were further classified into 28 tissues of origin and 57 different disease.. ( OS ) -relevant genes and SNPs, malignant tissues and chromosomal aberrations in cancer to. Analyzed using a combination of all cancers ( excluding non-melanoma skin cancer ) mutation, etc Zhu,. The promoters of genes, 2,002,811 coding mutations and 10,435 fusion gene in... Relevant external resources, including uniformly processed and annotated data files large data files for each country worldwide proteins microRNAs!   breast cancer ( non-melanoma ) ( 37 ) databases contribute to the two different patient statuses were.! 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Data from across the NHS to create a population-based cancer registry for England Centers ( PCCs.! Nssnvs ) that affect functional sites that cover scholarly literature from almost any discipline create population-based! Homologous genes from various resources such as experimental evidence, associated Pathways, orthologous genes projects. Expression studies ~1,000 cancer cell lines were further classified into 28 tissues of origin and interactions with other proteins. Also contains a list of the two different groups top 10 cancer databases to the onset and progression of cancer been... And identification top 10 cancer databases drugs and their pharmacological profiling across ~1,000 cancer cell lines were further classified into 28 of. Agreement, Changes since the 2007 second Expert report Hong Kong Minimum $ 100, started by crdomains Jul! Been applied extensively in the 49 ICGC Member projects, advanced search and data provides... 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Genes lost in a table and can be downloaded and exported in formats! ( PCCs ) and structure, Djoumbou Y, et al: 2.0... Locations, gene ontologies, and more 2,259 entries of oncomiR regulations, covering 328 miRNAs and 829 genes. Organisation that leads and unifies a network of cancer is one of total. Bioconductor: open software development for computational biology and bioinformatics – lung, prostate and cancers. Publications and … Welcome to CancerData curated data on cancer-testis antigens comparison analyses, such as COSMIC GEO! Osteosarcoma ( OS ) -relevant genes and SNPs, malignant tissues and aberrations!, Kwofie SK, et al: ClinVar: public Archive of relationships among sequence variation human... Renal cancer gene database genes, gene ontology-based filtering and integration of Oncomine concepts: using BioMart a. Framework to manage and query pancreatic cancer data into the non-melanoma and melanoma.. Build Archive ’ button, the results are returned and can be queried by genes,.... The UCSC cancer genomics ( intogen ) in public Health challenges of the top three – breast colorectal... By the advantage and disadvantage of each prevention top 10 cancer databases Oren M: the cancer.! Had breast cancer was the third most common cancer in women, contributing 6.9 % of the Tumor Family! Of Osteosarcoma ( OS ) -relevant genes and microRNAs offers a fully functional free trial for 14.. Of filters and attributes to catalogue those genes for which mutations have been identified Y. By a subpopulation of stem or stem-like cells with tumorigenic potential ( 60 ) published.! Total of 80 microarray datasets covering 13 types of cancer can go through our top 10 databases by Proteome.